Publications
October 4, 2021
An evaluation of cardiac health in the Spontaneously Hypertensive Rat Colony: Implications of evolutionary driven increases in concentric hypertrophy
Holjak EJB, Savinova I, Nelson VL, Ogilvie LM, Ng AM, Edgett BA, Platt MJ, Brunt KR, Ask K, Simpson JA. An evaluation of cardiac health in the Spontaneously Hypertensive Rat Colony: Implications of evolutionary driven increases in concentric hypertrophy, American Journal of Hypertension, 2021;, hpab155, https://doi.org/10.1093/ajh/hpab155
August 26, 2021
A new approach to improve the hemodynamic assessment of cardiac function independent of respiratory influence
Ogilvie, L.M., Edgett, B.A., Gray, S., Al-Mufty, S., Huber, J.S., Brunt, K.R., & Simpson, J.A. A new approach to improve the hemodynamic assessment of cardiac function independent of respiratory influence. Sci Rep 11, 17223 (2021). https://doi.org/10.1038/s41598-021-96050-y
October 21, 2020
Disruption of Physiological Rhythms Persist Following Cessation of Cigarette Smoke Exposure in Mice
Vanderstocken G*, Marrow JP*, Allwood MA, Stampfli MR, Simpson JA. Disruption of Physiological Rhythms Persist Following Cessation of Cigarette Smoke Exposure in Mice. Front Physiol. 2020 Oct 21;11:501383. doi: 10.3389/fphys.2020.501383. PMID: 33192539; PMCID: PMC7609783. *Denotes equal contribution.
September 3, 2020
Applications of a novel radiotelemetry method for the measurement of intrathoracic pressures and physiological rhythms in freely behaving mice
Foster AJ*, Marrow JP*, Allwood MA, Brunt KR, Simpson JA. Applications of a novel radiotelemetry method for the measurement of intrathoracic pressures and physiological rhythms in freely behaving mice. J Appl Physiol (1985). 2020 Oct 1;129(4):992-1005. doi: 10.1152/japplphysiol.00673.2019. Epub 2020 Sep 3. PMID: 32881619; PMCID: PMC7654688. *Denotes equal contribution.
July 11, 2020
Muscle and serum myostatin expression in type 1 diabetes
Dial, A.G., Monaco, C.M., Grafham, G.K., Romanova, N., Simpson, J.A., Tarnopolsky, M.A., Perry, C.G., Kalaitzoglou, E., & Hawke, T.J. (2020). Muscle and serum myostatin expression in type 1 diabetes. Physiological reports, 8(13), e14500. https://doi.org/10.14814/phy2.14500
April 21, 2020
Hemodynamic assessment of diastolic function for experimental models
Ogilvie, L. M., Edgett, B. A., Huber, J. S., Platt, M. J., Eberl, H. J., Lutchmedial, S., Brunt, K. R., & Simpson, J. A. (2020). Hemodynamic assessment of diastolic function for experimental models. American journal of physiology. Heart and circulatory physiology, 318(5), H1139–H1158. https://doi.org/10.1152/ajpheart.00705.2019
April 2, 2019
Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H2O2Â emission during impaired oxidative phosphorylation
Hughes, M.C., Ramos, S.V., Turnbull, P.C., Rebalka, I.A., Cao, A., Monaco, C.M., Varah, N.E., Edgett, B.A., Huber, J.S., Tadi, P., & Delfinis, L.J. (2019). Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H2O2 emission during impaired oxidative phosphorylation. Journal of cachexia, sarcopenia and muscle, 10(3), 643-661.
Chicago. https://doi.org/10.1002/jcsm.12405
January 23, 2019
Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy
Hughes, M.C., Ramos, S.V., Turnbull, P.C., Edgett, B.A., Huber, J.S., Polidovitch, N., Schlattner, U., Backx, P.H., Simpson, J.A., & Perry, C.G. (2020). Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy. The Journal of physiology, 598(7), 1377-1392. https://doi.org/10.1113/JP277306
May 15, 2018
Pathophysiological Mapping of Experimental Heart Failure: Left and Right Ventricular Remodeling in Transverse Aortic Constriction Is Temporally, Kinetically and Structurally Distinct
Platt, M. J., Huber, J. S., Romanova, N., Brunt, K. R., & Simpson, J. A. (2018). Pathophysiological Mapping of Experimental Heart Failure: Left and Right Ventricular Remodeling in Transverse Aortic Constriction Is Temporally, Kinetically and Structurally Distinct. Frontiers in physiology, 9, 472. https://doi.org/10.3389/fphys.2018.00472
March 31, 2018
Moderate and severe hypoxia elicit divergent effects on cardiovascular function and physiological rhythms
Allwood, M.A., Edgett, B.A., Eadie, A.L., Huber, J.S., Romanova, N., Millar, P.J., Brunt, K.R. and Simpson, J.A. (2018), Moderate and severe hypoxia elicit divergent effects on cardiovascular function and physiological rhythms. J Physiol, 596: 3391-3410. doi:10.1113/JP275945
June 1, 2017
Pulmonary Flow as an Improved Method for Determining Cardiac Output in Mice after Myocardial Infarction
Platt MJ, Huber JS, Brunt KR, Simpson JA. Pulmonary Flow as an Improved Method for Determining Cardiac Output in Mice after Myocardial Infarction. J Am Soc Echocardiogr. 2017;30(6):612-623.e1. doi:10.1016/j.echo.2017.02.008
May 17, 2017
Central-acting therapeutics alleviate respiratory weakness caused by heart failure–induced ventilatory overdrive
Foster, A. J., Platt, M. J., Huber, J. S., Eadie, A. L., Arkell, A. M., Romanova, N., Wright, D. C., Gillis, T. E., Murrant, C. L., Brunt, K. R., & Simpson, J. A. (2017). Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive. Science translational medicine, 9(390), eaag1303. https://doi.org/10.1126/scitranslmed.aag1303